A Study on Knowledge, Attitude, Practice about Hepatitis Infection and Its Awareness Among Pharmacy Students in Private Institution at Cuddalore, Tamilnadu

Saiprasath K, Usha GK2, Rajarajan, Yallappa

Narcolepsy, a chronic neurological disorder characterized by excessive daytime sleepiness and disrupted night-time sleep, significantly impacts the quality of life for affected individuals. While oral medications have been the mainstay of treatment, they often present challenges related to fluctuating drug levels, potential side effects, and adherence. In response, the development of transdermal drug delivery systems has emerged as a promising avenue for providing sustained and controlled therapeutic benefits. This review delves into the intricate realm of pharmaceutical formulation and manufacturing aspects that underpin the creation of effective transdermal patches for narcolepsy. The skin, acting as a sophisticated portal, presents both opportunities and obstacles for drug delivery. Overcoming the stratum corneum's barrier function requires meticulous formulation design, encompassing the selection of appropriate penetration enhancers, the development of advanced drug reservoirs, and the optimization of adhesive technologies. Furthermore, the precise control of drug release kinetics is paramount in narcolepsy, where consistent wakefulness is crucial. This necessitates the exploration of innovative manufacturing techniques, including microneedle fabrication, polymer matrix engineering, and advanced coating processes.

Keywords – Narcolepsy,Transdermal Drug Delivery Systems(TDDS), Microneedles, Penetration Enhancers, Nanocarriers